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CyanoacrylateGlueThree Years Later - Patient Results

  • 08
    By Katherine Kozlowski, Medical Author and contributor to Vein News and Veinsveinsveins.com

    Use of cyanoacrylate glue for the ablation of saphenous veins is gaining wider use around the world.

    Researchers from Germany, the United Kingdom, Denmark, and the Netherlands performed a 3-year study of patient outcomes after having cyanoacrylate treatment of refluxing great saphenous veins.

    70 patients were treated in the study. None of the patients used compression stockings post-procedure for 3 years. 64 patients (91%) successfully followed up 6-, 12-, 24-, and 36- months post-procedure.

    Rate of closure at 6-months: 91.4%
    Rate of closure at 12-months: 90.0%
    Rate of closure at 24-months: 88.5%
    Rate of closure at 36-months: 88.5%
    Average venous clinical severity scores (VCSS) decreased from 4.3 to .9 at baseline and 36-months, respectively.
    The use of cyanoacrylate glue for treatment of great saphenous vein reflux is an effective, minimally invasive option to reduce symptoms over an extended period of time.

    Proebstle T, Alm J, Dimitri S et al. Three-year follow-up results of the prospective European Multicenter Cohort Study on Cyanoacrylate Embolization for treatment of refluxing great saphenous veins. J Vasc Surg: Venous Lymphat Disord 2021; 9(2): 329-334.

    Dr Karamanoukian's comment:  In addition to FDA cleared cyanoacrylate products (VenaSeal), there are also "glues" that have been used in underdeveloped countries.  One such example is named "Turkish" glue and is sold in many countries around the world.   These products are not FDA approved for use in the United States.