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DVT prophylaxis in Covid-19 infected patients

  • 09
    by Katherine Kozlowski (Medical Writer for www.VeinsVeinsVeins.com) 

    Our colleague, Naomi Schwaitz receently reported on a study done by Karaali and colleagues in 
    Turkey who compared the number of deep vein thrombosis (DVT) cases during the quarantine period for COVID-19 to that of the year past (2019). 

    These researchers reported that despite the decrease in the total number of patients admitted to the hospital, there was a significant increase in the number of DVT patients.

    What remains unknown is what the
     incidence of deep vein thrombosis (DVT) is in critically ill COVID-19 patients who receive thrombosis prophylaxis. 

    Chen S and colleagues performed a retrospective study in the ICU who were critically ill with COVID-19 at Jinyintan Hospital in Wuhan, China. All patients had compression ultrasonography for identifying DVT. Firth logistic regression was used to examine the association of DVT with sex, age, hypoalbuminemia, D-dimer levels and SOFA score.

    The researchers found a high incidence of DVT in critically ill patients who were infecteed with COVID-19, despite the use of guideline-recommended pharmacologic thromboprophylaxis. The presence of hypoalbuminemia, higher SOFA score, and elevated D-dimer were independent risk factors for DVT.

    Chen S, Zhang D, Zheng T, Yu Y, Jiang J.  DVT incidence and risk factors in critically-ill patients with Covid-19. J Thromb Thrombolysis 2020; 30: 1-7.